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A case report on multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 infection
Roshan Bhandari1, Richa Paudyal1, Abhigya Paudyal2
1Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University Kathmandu Nepal.
Insights
Early recognition and treatment of Multisystem Inflammatory Syndrome in Children (MIS-C) linked to COVID-19 are vital. Prompt intervention with IVIG and steroids significantly improved a severe pediatric case, highlighting the need for clinical vigilance.
Area of Science:
- Pediatrics
- Infectious Diseases
- Cardiology
Background:
- COVID-19 infection can trigger severe inflammatory responses in children.
- Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare but serious complication.
- Early identification and management are critical for favorable outcomes.
Key Clinical Message:
Early recognition and treatment of Multisystem Inflammatory Syndrome in Children (MIS-C) within the context of COVID-19 infection is crucial for improved outcomes. Prompt intervention with IVIG and steroids leads to significant improvement in a severe case of MIS-C. Clinicians should be vigilant for MIS-C symptoms and initiate timely management.
Abstract:
We report a case involving a fourteen-year-old male with COVID-19 infection who developed multisystem inflammatory disease. A previously healthy child presented with a history of 10 days of fever and cough, along with diarrhea, and vomiting for 3 days. His COVID-19 infection was confirmed through Polymerase Chain Reaction (PCR), and the laboratory values were remarkable for high levels of C-reactive protein, D-dimers, B-type natriuretic peptide (BNP), and troponin I. He developed circulatory shock on the second day of the presentation and needed inotropic support. Steroids and intravenous immunoglobulin (IVIG) were started in light of Multisystem Inflammatory Syndrome in Children (MIS-C), which improved his condition. Thus, during the management of COVID-19 infection, early detection and a careful clinical characterization for MIS-C are essential.
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