Towards building a trustworthy pipeline integrating Neuroscience Gateway and Open Science Chain

Area of Science:

• Neuroscience
• Data Science
• Cyberinfrastructure

Background:

• Scientific datasets and their metadata, including provenance, require secure preservation during evolution and reuse to ensure integrity.
• Verifying and sharing data and metadata efficiently is crucial for scientific data reuse and reproducibility.
• The Open Science Chain (OSC) and Neuroscience Gateway (NSG) are cyberinfrastructure solutions addressing these needs.

Purpose of the Study:

• To present the first study integrating the OSC and NSG frameworks.
• To demonstrate secure tracking and verification of provenance metadata for neurophysiological signal data analysis.
• To study brain network dynamics using the Neuro-Integrative Connectivity tool within the integrated framework.

Main Methods:

• Utilized a consortium blockchain (OSC) for secure metadata integrity and verification.
• Employed a web portal (NSG) for computational data analysis on high-performance computing resources.
• Integrated OSC and NSG to automatically preserve and verify research workflow artifacts.

Main Results:

• Successfully tracked provenance of neurophysiological signal data analysis.
• Demonstrated secure preservation and verification of data and metadata integrity.
• Enabled independent verification of datasets and promoted data reuse and reproducibility.

Conclusions:

• The integrated OSC-NSG framework provides an efficient and secure solution for managing scientific data provenance.
• This approach enhances the reliability of research workflows, particularly in neuroscience.
• The study highlights the potential of blockchain and cyberinfrastructure for advancing open science principles.