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Updated: Jun 29, 2025

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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
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Implementation of a Trauma Bay Checklist Improves Antibiotic Prophylaxis Compliance in Open Extremity Fractures
Robert D Luke1, Casey P Balio2, Claire K Foley3
1Department of Surgery, Eastern Virginia Medical School, Norfolk, VA, USA.
The American Surgeon
|April 8, 2024
Summary
Implementing the MARTY checklist improved timely antibiotic administration for open fractures. However, compliance remains a challenge for patients with severe injuries, highlighting areas for future trauma care improvement.
Area of Science:
- Trauma Surgery
- Patient Safety
- Antibiotic Stewardship
Background:
- American College of Surgeons (ACS) guidelines recommend antibiotics within 1 hour for open fractures.
- Checklists enhance safety and compliance in surgical environments.
- The study evaluated the MARTY checklist for antibiotic administration in open extremity fractures.
Purpose of the Study:
- To assess the impact of the MARTY trauma bay checklist on antibiotic administration timeliness.
- To improve adherence to best practices for open fracture management.
Main Methods:
- Retrospective pre-post study design.
- Analysis of trauma alerts for open fractures from 2021 (pre-MARTY) and 2022 (post-MARTY).
- Comparison of antibiotic administration rates within 1 hour and within the trauma bay.
Main Results:
- Antibiotic administration within 1 hour increased from 57.5% to 65.5% post-MARTY.
- Administration within the trauma bay rose from 46.0% to 54.5% post-MARTY.
- Adjusted models showed significantly higher odds of timely antibiotic administration post-MARTY (OR=1.654, P=.038).
Conclusions:
- The MARTY checklist implementation led to improved compliance with antibiotic administration guidelines.
- Compliance is still suboptimal for patients with higher injury severity scores.
- Findings can inform strategies for enhancing trauma care protocols.
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