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Updated: Jun 28, 2025

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Ventricular Thrombus Formation Caused by Subendomyocardial Inflammation in Eosinophilic Granulomatosis With
Naoyuki Takahashi1, Takenori Ikoma1, Atsushi Sakamoto1
1Division of Cardiology, Internal Medicine III, Hamamatsu University School of Medicine, Hamamatsu, Japan.
JACC. Case Reports
|April 11, 2024
Abstract:
Cardiac involvement of eosinophilic granulomatosis with polyangiitis is a rare but life-threatening complication. We present a case of eosinophilic granulomatosis with polyangiitis with moderately impaired ventricular function forming a ventricular thrombus. Pathological assessment of endomyocardial biopsy specimen revealed aggregated eosinophils in the subendocardium, suggesting ventricular endothelial damage leading to thrombus formation.
Keywords:
cardiac magnetic resonanceendomyocardial biopsyeosinophilic granulomatous with polyangiitisventricular thrombus
