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Skeletal Muscle Relaxants: Therapeutic Uses01:31

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Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
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Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review.

John Kiel1,2, Andres I Applewhite3, Tais G O Bertasi4

  • 1Department of Emergency Medicine, University of Florida, Jacksonville, Florida.

Clinical Medicine & Research
|April 12, 2024
PubMed
Summary

Ketorolac injections offer a potentially safe alternative to corticosteroid injections for musculoskeletal pain. More research is needed to fully understand ketorolac

Keywords:
Anti-inflammatory agentsArthritisGlucocorticoidsKetorolacMusculoskeletal diseasesNonsteroidal

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Area of Science:

  • Orthopedics
  • Pharmacology
  • Rheumatology

Background:

  • Musculoskeletal conditions frequently receive corticosteroid injections.
  • Parenteral nonsteroidal anti-inflammatory drugs (NSAIDs), like ketorolac, offer an alternative injectant.
  • Commonly treated conditions include shoulder, hip, and knee issues.

Purpose of the Study:

  • To review the current literature on the efficacy of ketorolac injections for musculoskeletal diseases.
  • To evaluate ketorolac as a potential alternative to corticosteroids for joint pain.

Main Methods:

  • A comprehensive literature review was performed.
  • Studies focusing on ketorolac injection efficacy in musculoskeletal conditions were analyzed.

Main Results:

  • Evidence supports ketorolac injection efficacy in subacromial bursitis, adhesive capsulitis, and hip/knee osteoarthritis.
  • Ketorolac presents a potential alternative to glucocorticoids, considering their systemic effects.

Conclusions:

  • Ketorolac injection may be a safe and effective option for certain musculoskeletal conditions.
  • Further research is necessary to elucidate the precise effects of ketorolac during inflammation.