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Updated: Jun 28, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Obtaining New Biocompatible Composite Materials with Antibacterial Properties Based on Diatomite and Biologically
Saule Kabieva1, Gaziza Zhumanazarova1, Rymgul Zhaslan1
1Department of Chemical Technology and Ecology, Karaganda Industrial University, Temirtau 101400, Kazakhstan.
Abstract:
This study aimed to create new composite materials based on diatomite-a non-organic porous compound-through its surface modification with bioactive organic compounds, both synthetic and natural. Chloramphenicol, tetrahydroxymethylglycoluril and betulin were used as modifying substances. Composite materials were obtained by covering the diatomite surface with bioactive substance compounds as a solution and material dispersion in it. The materials were characterized by IR spectroscopy, SEM and X-ray photoelectron spectroscopy. For the biocomposites, the hemolytic effect, plasma proteins' adsorption on the surface and the antibacterial activity of the obtained materials were studied. Results show that the obtained materials are promising for medicine and agriculture.

