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Acute Respiratory Failure-II

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Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy

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Hypoxic-ischaemic encephalopathy code: A systematic review for resource-limited settings.

Alfredo Garcia-Alix¹, Juan Arnaez², Gemma Arca³

¹Neurología Neonatal, NeNe Foundation, Madrid, Spain; Neonatología, Ibero-American Society of Neonatology (SIBEN), New Jersey, USA.

Anales De Pediatria

|April 13, 2024

Summary

This review presents the "HIE Code," a set of evidence-based recommendations for managing hypoxic-ischaemic encephalopathy (HIE) in infants born in resource-limited settings, aiming to improve outcomes despite limitations.

Keywords:

Convulsiones neonatales Electroencephalographic monitoring Encefalopatía hipóxico-isquémica Encefalopatía neonatal Entornos con recursos limitados Hipotermia terapéutica Hypoxic-ischaemic encephalopathy Low-middle-income countries Monitorización electroencefalográfica Neonatal encephalopathy Neonatal seizures Neonate Neonato Países con bajos-medios recursos Resource-limited settings Therapeutic hypothermia

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The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

Published on: November 19, 2008

Area of Science:

Neonatal Medicine
Neurology
Global Health

Background:

Hypoxic-ischaemic encephalopathy (HIE) affects 96% of infants in resource-limited settings.
Standard HIE care (therapeutic hypothermia, EEG, MRI) is unavailable in these areas.
Current knowledge can optimize HIE care even with resource constraints.

Approach:

Systematic review to develop evidence-based recommendations for HIE care.
The "HIE Code" provides feasible practices for resource-limited settings.
Recommendations cover prevention, resuscitation, diagnosis, treatment, and family care.

Key Points:

The "HIE Code" addresses critical aspects of HIE management.
Focuses on practical interventions adaptable to low-resource environments.
Aims to reduce HIE-related comorbidity and improve neurodevelopmental outcomes.

Conclusions:

The "HIE Code" offers a framework for improving HIE infant care globally.
Evidence-based guidelines are crucial for optimizing outcomes in resource-limited settings.
Implementing the "HIE Code" can mitigate risks and enhance neurodevelopmental trajectories.