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What Is "Key Information"? Consideration of the Reasons People Do or Do Not Take Part in Research
1Clinical research coordinator of medical ethics and health policy at the Perelman School of Medicine at the University of Pennsylvania.
Abstract:
We performed a qualitative review of 50 consent forms posted on Clinicaltrials.gov, examining the content of key information sections. We found that key information disclosures are typically focused on procedures, risks, potential benefits, and alternatives. Drawing upon reviews of the large literature examining the reasons people do or do not take part in research, we propose that these disclosures should be based more directly on what we know to be the real reasons why people choose to take part or refuse participation. We propose key information language for consideration by researchers and institutional review boards.
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