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SARS-CoV-2 Infection Among Newborn Infants: A Scoping Review
Liji Mathew1, Mia Schmolze, Kathleen V Carter
1Schools of Nursing (Dr Mathew) and Medicine (Mss Schmolze and Carter), University of Texas Rio Grande Valley, Edinburg, Texas.
Summary
Maternal SARS-CoV-2 infection may impact newborns. This review found few studies on infants born >37 weeks gestation with COVID-19, highlighting community transmission post-discharge.
Area of Science:
- Neonatal care
- Infectious disease epidemiology
- Maternal-fetal medicine
Background:
- Maternal SARS-CoV-2 infection poses risks for preterm infants.
- Limited research exists on full-term infants born to SARS-CoV-2 positive mothers.
Purpose of the Study:
- Identify research gaps on SARS-CoV-2 positive infants born >37 weeks gestation in the U.S.
- Synthesize current literature on this specific neonatal population.
Main Methods:
- Scoping review of CINAHL, Ovid MEDLINE, and Web of Science databases.
- Inclusion of case reports, case series, cohort, and retrospective studies.
- Screening of 4262 citations, with 12 articles meeting eligibility criteria.
Main Results:
- Identified literature gaps concerning neonatal SARS-CoV-2 infection up to one month of age.
- Observed a higher prevalence of community-acquired SARS-CoV-2 in infants post-discharge.
- Highlighted a scarcity of U.S.-based studies on SARS-CoV-2 positive infants born >37 weeks gestation.
Conclusions:
- Further follow-up studies are crucial for infants born >37 weeks gestation with SARS-CoV-2, particularly within the first 30 days of life.
- Emphasized the importance of discharge education to mitigate community transmission and reduce healthcare visits.
- Underscored the need for more research on the long-term outcomes of these infants.
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