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Partial nephrectomy in multiple mixed epithelial and stromal tumors (MEST)
Nasser Simforoosh1, Mohammad Sajjad Zabihi1, Mehdi Dadpour1
1Shahid Beheshti University of Medical Sciences, Shahid Labbafinejad Medical Center, Center of Excellence in Urology, Urology and Nephrology Research Center, Tehran, Iran.
Urology Case Reports
|April 22, 2024
Summary
Mixed epithelial and stromal tumors (MEST) are rare kidney tumors. This case highlights successful surgical management of simultaneous bilateral MESTs, demonstrating good patient outcomes and renal function preservation.
Area of Science:
- Nephrology
- Oncology
- Surgical Pathology
Background:
- Mixed epithelial and stromal tumors (MEST) are uncommon renal neoplasms.
- These tumors often present diagnostic challenges, mimicking malignant renal masses.
- Surgical resection is the primary treatment modality for MEST.
Observation:
- A 35-year-old female presented with two distinct, large solid-cystic renal masses in the left kidney.
- The masses exhibited contrast enhancement, suggesting potential malignancy.
- The patient underwent surgical management via partial nephrectomy for both lesions.
Findings:
- Microscopic examination confirmed the diagnosis of MEST.
- The tumors were characterized by solid components and cysts lined by flattened to cuboidal epithelium.
- Post-operative follow-up revealed preserved renal function and no signs of recurrence.
Implications:
- This case underscores the importance of considering MEST in the differential diagnosis of solid-cystic renal masses.
- Partial nephrectomy can be an effective treatment, preserving renal function.
- Successful surgical outcomes are achievable for complex MEST presentations.
