From flesh to bones: Multi-omics approaches in forensic science

Area of Science:

• Forensic Science
• Biotechnology
• Genomics

Background:

• Omics techniques generate high-throughput biomolecular data, revolutionizing biological system studies.
• Applications span personalized medicine to forensic sciences.
• Multi-omics integration is established in biomedicine but underexplored in forensics.

Purpose of the Study:

• To provide an overview of omics analytical platforms for forensic applications.
• To emphasize the use of omics in cadaver identification and cause of death determination.
• To critically analyze computational integration of omics approaches in forensic investigations.

Main Methods:

• Review of state-of-the-art analytical platforms in omics research.
• Focus on applications within the forensic field.
• Analysis of computational integration and multi-omics techniques.

Main Results:

• Omics techniques offer advanced capabilities for forensic investigations.
• Multi-omics approaches show significant potential for cadaver identification.
• Computational integration is key to unlocking the full potential of multi-omics in forensics.

Conclusions:

• Omics technologies are transforming forensic science.
• Multi-omics integration provides novel insights for identifying cadavers and causes of death.
• Further research into computational integration will enhance forensic applications.