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Related Concept Videos

Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

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Related Experiment Video

Updated: Jun 16, 2026

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
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Digital Remote Monitoring Using an mHealth Solution for Survivors of Cancer: Protocol for a Pilot Observational

Pasquale F Innominato1,2,3, Jamie H Macdonald4, Wendy Saxton5

  • 1Oncology Department, Ysbyty Gwynedd, Betsi Cadwaladr University Health Board, Bangor, United Kingdom.

JMIR Research Protocols
|April 30, 2024
PubMed
Summary

This pilot study assesses mobile health (mHealth) app feasibility for cancer survivors, monitoring lifestyle factors like physical activity and sleep. Findings will inform future digital interventions for improved survivorship care.

Keywords:
actigraphyartificial intelligencecancercircadiandigital healthmHealthmobile healthmobile phoneremote monitoringsurvivorship

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Area of Science:

  • Digital Health
  • Oncology Supportive Care
  • Lifestyle Medicine

Background:

  • Healthy lifestyle interventions positively impact cancer outcomes and survivorship.
  • Physical activity, sleep, and diet are crucial for cancer survivor well-being.
  • Mobile health (mHealth) apps offer potential for tailored lifestyle support.

Purpose of the Study:

  • To assess the feasibility of multidimensional longitudinal monitoring using mHealth in cancer survivors.
  • Primary objective: Evaluate user engagement (compliance) with the mHealth monitoring solution.
  • Secondary objectives: Record clinically relevant subjective and objective patient data.

Main Methods:

  • Observational pilot study in Bangor, UK, enrolling up to 100 adult cancer survivors.
  • 16-week monitoring period using a dedicated app for self-reported data and a smartwatch for objective data.
  • Primary endpoint: Feasibility (acceptability of mHealth monitoring); Secondary endpoints: Patient-reported outcomes and physiological measures.

Main Results:

  • Study accrual planned from January 2024 to June 2024 as part of the EU-funded GATEKEEPER project.
  • Hypothesis: At least 50% of participants will engage with the app weekly for 8 out of 16 weeks.
  • Data collection includes self-reported behaviors, validated questionnaires (e.g., ESAS), and objective measures (e.g., step counts).

Conclusions:

  • This pilot study will determine the feasibility of remote multidimensional monitoring for cancer survivors.
  • Compliance with mHealth app and smartwatch use is key to developing innovative digital interventions.
  • Results will guide the development of future mHealth strategies for improved cancer survivorship care.