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First Case Report of Bilateral Parotid Lymphoepithelial Carcinoma
Willer Everton Feitosa Meneses1, Pedro Henrique Cunha Lima DO Rego1, Valdenor Neves Feitosa Junior1
1Head and Neck Surgery Department, Santa Casa da Misericórdia de Fortaleza Hospital, Fortaleza, Brazil.
Cancer Diagnosis & Prognosis
|May 6, 2024
Summary
Bilateral parotid lymphoepithelial carcinoma (LEC) is rare. This case highlights the unusual presentation of this malignant salivary gland tumor in a 35-year-old man, requiring adjuvant radiotherapy.
Area of Science:
- Oncology
- Head and Neck Surgery
- Pathology
Background:
- Parotid gland neoplasms are uncommon, with 20% being malignant.
- Lymphoepithelial carcinoma (LEC) is a rare malignant salivary gland tumor, accounting for 0.4% of head and neck malignancies.
- LEC can exhibit heterogeneous features and distinctive behavior.
Purpose of the Study:
- To report a rare case of bilateral parotid lymphoepithelial carcinoma.
- To discuss the diagnostic challenges and treatment of this unusual presentation.
Main Methods:
- A 35-year-old male patient presented with a painless cervical mass.
- Diagnostic investigations revealed bilateral parotid involvement and systemic lymphadenopathy.
- Adjuvant radiotherapy was administered.
Main Results:
- The patient was diagnosed with bilateral parotid lymphoepithelial carcinoma.
- The disease involved contralateral parotid and systemic lymph nodes.
- Adjuvant radiotherapy was deemed necessary.
Conclusions:
- Bilateral parotid LEC can present with heterogeneous and distinctive features.
- This case underscores the importance of thorough investigation for suspected salivary gland malignancies.
- Management may involve adjuvant radiotherapy for advanced disease.

