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Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
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Renal Failure Without Hemodialysis Is a Risk Factor for Postoperative Complications in Colorectal Cancer Surgery
Takaaki Fujimoto1, Shigetaka Inoue1, Taketo Matsunaga1
1Department of Surgery, Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan.
Cancer Diagnosis & Prognosis
|May 6, 2024
Summary
Renal failure (RF) significantly increases postoperative complications and hospital stay for colorectal cancer (CRC) patients undergoing surgery. Careful perioperative management is crucial for this high-risk group.
Area of Science:
- Oncology
- Nephrology
- Surgical Outcomes
Background:
- Surgical outcomes for colorectal cancer (CRC) patients with renal failure (RF) require further clarification.
- Investigating the impact of RF on CRC surgical outcomes is essential for patient care.
Purpose of the Study:
- To determine the effect of renal failure (RF) on surgical outcomes in patients diagnosed with colorectal cancer (CRC).
Main Methods:
- Retrospective analysis of 633 patients undergoing colorectal resection for CRC (January 2017 - December 2021).
- Comparison of outcomes between patients with and without RF (defined as eGFR < 30 mL/min/1.73m²).
Main Results:
- Renal failure (RF) was identified in 7% of patients and is a significant risk factor for postoperative complications (OR=2.19, p=0.0284).
- Patients with RF exhibited higher comorbidity, poorer ASA status, lower hemoglobin and PNI levels.
- RF patients experienced significantly more postoperative complications (p=0.016) and longer hospital stays (p<0.01).
Conclusions:
- Renal failure (RF) is associated with adverse surgical outcomes in colorectal cancer (CRC) patients.
- Enhanced perioperative management strategies are necessary for CRC patients with renal compromise.
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