[Ultrastructural pathology of the liver in shock]

Ultrastructural findings in shock liver are in general very similar to data in the literature concerning experimental ischaemia in the animal. It is firstly a cellular disease which leads to a tissue disease, reflected morphologically by definitive and irreversible signs in the absence of hepatocellular regeneration. Assessment on the cellular scale of lesions of ischaemia may be used to define the potentially reversible nature of certain signs and should be adpated to the study of the cellular effects of therapeutic measures. By contrast, in practical terms it cannot be used for the quantitative assessment of the spatial extent of lesions within the hepatic acinus.