[Detection of T cell independent B cell maturation disorder in cocultivation studies in systemic lupus erythematosus]
Related Experiment Video
Updated: Aug 13, 2026

12:04
The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Abstract:
Lymphocyte coculture experiments were performed in a case of monozygotic twins, discordant for SLE. Lack of responsiveness to T-cell-dependent and independent B-cell stimulation gave evidence of an intrinsic B-cell defect in the SLE twin.

