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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Related Experiment Video

Updated: Jun 26, 2025

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

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Herpes Simplex Virus Dacryoadenitis Preceding Skin Vesicles.

Yasaman Ataei1, Nina S Boal, Neda Esmaili

  • 1Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.

Ophthalmic Plastic and Reconstructive Surgery
|May 9, 2024
PubMed
Summary
This summary is machine-generated.

Herpes simplex virus (HSV) orbital infection is rare. This case highlights HSV dacryoadenitis preceding skin lesions in an immunocompetent patient, emphasizing prompt antiviral treatment.

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Virology

Background:

  • Orbital involvement by herpes simplex virus (HSV) is uncommon.
  • Early diagnosis and treatment are crucial for managing ocular infections.

Observation:

  • An immunocompetent patient presented with preseptal edema, erythema, decreased vision, and dacryoadenitis.
  • Initial symptoms appeared before characteristic skin vesicles and without corneal dendrites.
  • Empiric antibiotic therapy was ineffective.

Findings:

  • The patient developed skin vesicles, and ocular surface swabs confirmed herpes simplex virus-1 (HSV-1) via nucleic acid amplification.
  • Oral antiviral therapy led to rapid clinical improvement.

Implications:

  • This case suggests HSV dacryoadenitis can precede cutaneous manifestations in immunocompetent individuals.
  • Highlights the importance of considering viral etiologies in orbital inflammation, even without typical signs.
  • Prompt diagnosis and antiviral treatment are key for favorable outcomes in atypical HSV presentations.