Persistent lower respiratory disease in children

American Family Physician
|September 1, 1985
PubMed

Insights

Diagnosing persistent lower respiratory disease in children requires a systematic approach. Common causes include asthma, viral pneumonia, and foreign body aspiration, but rare conditions must also be considered.

Area of Science:

  • Pediatrics
  • Pulmonology
  • Diagnostic Medicine

Background:

  • Recurrent or persistent lower respiratory disease in children presents with diverse clinical manifestations.
  • Identifying the underlying cause is crucial for effective management and improved patient outcomes.

Purpose of the Study:

  • To outline a systematic, stepwise approach for evaluating children with persistent lower respiratory disease.
  • To highlight common and rare differential diagnoses for pediatric lower respiratory symptoms.

Main Methods:

  • Systematic review of diagnostic strategies for pediatric lower respiratory conditions.
  • Analysis of common etiologies including reactive airways disease, prolonged viral pneumonia, and foreign body aspiration.
  • Consideration of a broad spectrum of less common differential diagnoses.

Main Results:

  • Persistent lower respiratory symptoms in children necessitate a comprehensive diagnostic workup.
  • Reactive airways disease (asthma), prolonged viral pneumonia, and foreign body aspiration are frequent causes.
  • A lengthy list of rare conditions also contributes to the differential diagnosis.

Conclusions:

  • A structured, stepwise evaluation is essential for diagnosing persistent lower respiratory disease in children.
  • The diagnostic process must encompass common etiologies and a wide range of rare possibilities.
  • Systematic assessment ensures accurate diagnosis and guides appropriate therapeutic interventions.

Related Concept Videos

Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...