Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Transcription Factors02:16

Transcription Factors

75.8K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
75.8K
General Transcription Factors01:30

General Transcription Factors

5.2K
Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
5.2K
Eukaryotic Transcription Activators02:42

Eukaryotic Transcription Activators

11.0K
Transcription activators are proteins that promote the transcription of genes from DNA to RNA. In most cases, these proteins contain two separate domains ‒ a domain that binds to DNA and a domain for activating transcription; however, in some cases, a single domain is responsible for both binding and activation of transcription, as seen in the glucocorticoid receptor and MyoD.
The binding domains are capable of recognizing and interacting with regulatory sequences on the DNA. These...
11.0K
RNA Polymerase II Accessory Proteins02:36

RNA Polymerase II Accessory Proteins

9.2K
Proteins that regulate transcription can do so either via direct contact with RNA Polymerase or through indirect interactions facilitated by adaptors, mediators, histone-modifying proteins, and nucleosome remodelers. Direct interactions to activate transcription is seen in bacteria as well as in some eukaryotic genes. In these cases, upstream activation sequences are adjacent to the promoters, and the activator proteins interact directly with the transcriptional machinery. For example, in...
9.2K
Combinatorial Gene Control02:33

Combinatorial Gene Control

8.3K
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
8.3K
Cell Signaling in Plants01:25

Cell Signaling in Plants

5.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Geminivirus-Induced Reprogramming of Plant Defense Mechanisms: Molecular Insights and Research Frontiers.

Annual review of virology·2026
Same author

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas.

Plant biotechnology journal·2026
Same author

Delineating microRNA169-Nuclear Factor Y-Subunit A Module for Its Potential Implications in Crop Improvement.

Plant, cell & environment·2025
Same author

Millets for a sustainable future.

Journal of experimental botany·2024
Same author

Diverse roles of phytohormonal signaling in modulating plant-virus interactions.

Journal of experimental botany·2024
Same author

Author Correction: Tomato 26S Proteasome subunit RPT4a regulates ToLCNDV transcription and activates hypersensitive response in tomato.

Scientific reports·2024

Related Experiment Video

Updated: Jun 26, 2025

Investigating Interactions Between Histone Modifying Enzymes and Transcription Factors in vivo by Fluorescence Resonance Energy Transfer
11:33

Investigating Interactions Between Histone Modifying Enzymes and Transcription Factors in vivo by Fluorescence Resonance Energy Transfer

Published on: October 14, 2022

1.6K

Decoding the functionality of plant transcription factors.

Pinky Dhatterwal1, Namisha Sharma2, Manoj Prasad1,3,4

  • 1National Institute of Plant Genome Research, New Delhi, India.

Journal of Experimental Botany
|May 18, 2024
PubMed
Summary
This summary is machine-generated.

Plant transcription factors (TFs) regulate gene expression for stress tolerance and growth. Understanding TF mechanisms, including their dual activation/repression roles, is key for crop improvement and adaptation.

Keywords:
cis-regulatory codeAlternative splicingLLPSchromatin architecturedual functionalitynon-coding RNApost-transcriptional and translational modificationssignal specificitytranscription factors

More Related Videos

Enhanced Yeast One-hybrid Screens To Identify Transcription Factor Binding To Human DNA Sequences
11:25

Enhanced Yeast One-hybrid Screens To Identify Transcription Factor Binding To Human DNA Sequences

Published on: February 11, 2019

7.9K
Determination of Tripartite Interaction between Two Monomers of a MADS-box Transcription Factor and a Calcium Sensor Protein by BiFC-FRET-FLIM Assay
14:34

Determination of Tripartite Interaction between Two Monomers of a MADS-box Transcription Factor and a Calcium Sensor Protein by BiFC-FRET-FLIM Assay

Published on: December 25, 2021

3.7K

Related Experiment Videos

Last Updated: Jun 26, 2025

Investigating Interactions Between Histone Modifying Enzymes and Transcription Factors in vivo by Fluorescence Resonance Energy Transfer
11:33

Investigating Interactions Between Histone Modifying Enzymes and Transcription Factors in vivo by Fluorescence Resonance Energy Transfer

Published on: October 14, 2022

1.6K
Enhanced Yeast One-hybrid Screens To Identify Transcription Factor Binding To Human DNA Sequences
11:25

Enhanced Yeast One-hybrid Screens To Identify Transcription Factor Binding To Human DNA Sequences

Published on: February 11, 2019

7.9K
Determination of Tripartite Interaction between Two Monomers of a MADS-box Transcription Factor and a Calcium Sensor Protein by BiFC-FRET-FLIM Assay
14:34

Determination of Tripartite Interaction between Two Monomers of a MADS-box Transcription Factor and a Calcium Sensor Protein by BiFC-FRET-FLIM Assay

Published on: December 25, 2021

3.7K

Area of Science:

  • Plant molecular biology
  • Genetics
  • Biochemistry

Background:

  • Transcription factors (TFs) are crucial regulators of gene expression in plants.
  • They balance growth and stress tolerance, vital for survival in adverse environments.
  • Understanding TF mechanisms is essential for deciphering plant development and environmental responses.

Purpose of the Study:

  • To provide a comprehensive understanding of factors and mechanisms governing plant TF activity.
  • To explore the functional duality of TFs (activation/repression) and its implications.
  • To highlight the practical applications of TF knowledge in molecular breeding for crop optimization.

Main Methods:

  • Literature review of current research on plant transcription factors.
  • Analysis of studies investigating TF regulatory networks.
  • Examination of research on TF functional duality and its impact on gene expression.

Main Results:

  • TFs modulate gene expression to manage the trade-off between plant growth and stress tolerance.
  • TF activity is influenced by various intrinsic and extrinsic factors.
  • TFs exhibit functional duality, switching between activation and repression modes to fine-tune gene expression.

Conclusions:

  • Understanding TF mechanisms, especially their dual nature, is critical for plant adaptation and survival.
  • This knowledge has direct applications in developing improved crop varieties through molecular breeding.
  • TF duality is a key mechanism for cell fate decisions and adaptive stress responses in plants.