Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Network Formation Dynamics in Thiol-ene Crosslinked Hyaluronic Acid Hydrogels: Design Principles for In Vitro Tissue Models.

bioRxiv : the preprint server for biology·2026
Same author

Enzymatic Methods for Assembling and Modifying Hydrogel Biomaterials.

Regenerative engineering and translational medicine·2026
Same author

A robust and user-agnostic step-emulsion platform for scalable microgel fabrication.

bioRxiv : the preprint server for biology·2026
Same author

De novo design of protein nanoparticles with integrated functional motifs.

bioRxiv : the preprint server for biology·2026
Same author

Suspended Tissue Engineering with Assemblable Microfluidics (STEAM).

bioRxiv : the preprint server for biology·2025
Same author

Boolean Logic-Based Controlled Release of Bioactive Proteins with Diversified Inputs.

Angewandte Chemie (International ed. in English)·2025

Related Experiment Video

Updated: Jun 26, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

7.8K

PhoCoil: An Injectable and Photodegradable Single-component Recombinant Protein Hydrogel for Localized Therapeutic

Nicole E Gregorio1, Cole A DeForest1,2,3,4,5,6

  • 1Department of Bioengineering, University of Washington.

Biorxiv : the Preprint Server for Biology
|May 20, 2024
PubMed
Summary

Researchers developed PhoCoil, a tunable recombinant hydrogel. This injectable biomaterial offers precise control over degradation using visible light, advancing tissue engineering and drug delivery.

More Related Videos

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.3K
Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model
08:43

Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model

Published on: February 7, 2018

7.6K

Related Experiment Videos

Last Updated: Jun 26, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

7.8K
An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

17.3K
Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model
08:43

Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model

Published on: February 7, 2018

7.6K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Hydrogels are promising for 3D cell culture and drug delivery but face limitations in tunability and bioinstructivity.
  • Natural protein hydrogels offer biocompatibility but limited customization.
  • Synthetic polymer hydrogels lack inherent biological cues.

Conclusions:

  • PhoCoil offers a molecularly defined, user-programmable platform mimicking the extracellular matrix.
  • The tunable and injectable nature of PhoCoil, combined with light-triggered degradation, presents significant advantages.
  • This novel hydrogel is poised to enable advancements in tissue engineering and regenerative medicine applications.