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Updated: Jun 25, 2025

Multi-modal Imaging of Angiogenesis in a Nude Rat Model of Breast Cancer Bone Metastasis Using Magnetic Resonance Imaging, Volumetric Computed Tomography and Ultrasound

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Published on: August 14, 2012

Imaging Approaches in Cancer Biology.

Nirakar Rajbhandari^1,2, Emily Diaz^1,2, Marcie Kritzik³

¹Departments of Pharmacology and Medicine, University of California San Diego School of Medicine, La Jolla, California 92093, USA.

Cold Spring Harbor Perspectives in Medicine

|May 21, 2024

Summary

This summary is machine-generated.

Understanding cancer cell dynamics in vivo is crucial. Emerging imaging strategies visualize cancer cells within their microenvironment to reveal growth mechanisms and potential therapeutic targets.

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

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Published on: July 21, 2018

Area of Science:

Oncology
Cell Biology
Biomedical Imaging

Background:

Most cancer research focuses on cellular and molecular aspects, neglecting in vivo cancer cell behavior.
Knowledge of cancer cell dynamics within the living microenvironment is limited.

Purpose of the Study:

To develop strategies for visualizing cancer cells within their microenvironment.
To understand the mechanisms controlling cancer initiation, growth, and metastasis.
To identify how microenvironmental interactions influence cancer progression and could be targeted.

Main Methods:

Discussing emerging work on visualizing cancer cell function in vivo.
Focusing on imaging cancer cells within the context of the living microenvironment.

Main Results:

Highlighting the importance of visualizing dynamic cancer cell behavior.
Emphasizing the role of microenvironmental interactions in aberrant cancer growth.

Conclusions:

Developing in vivo imaging is essential for understanding cancer progression.
Visualizing cancer cell-microenvironment interactions can reveal new therapeutic targets.