Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breast Cancer Risk and Screening in Active Duty Military Members and Veterans.

Journal of breast imaging·2026
Same author

Appropriateness of acute breast symptom recommendations provided by ChatGPT.

Clinical imaging·2025
Same author

A pilot study incorporating HER2-directed dendritic cells into neoadjuvant therapy of early stage HER2+ER- breast cancer.

NPJ breast cancer·2025
Same author

Cystic Breast Disease: What to Do When It's Not So Cystic.

Journal of breast imaging·2025
Same author

Presurgical Upgrade Prediction of DCIS to Invasive Ductal Carcinoma Using Time-dependent Deep Learning Models with DCE MRI.

Radiology. Artificial intelligence·2024
Same author

Variability in Mammography Quality Assessment After Implementation of Enhancing Quality Using the Inspection Program (EQUIP).

Journal of breast imaging·2024
Same journal

Orbital Imaging.

Radiologic clinics of North America·2026
Same journal

Imaging, Management, and Treatment of Orbital Trauma.

Radiologic clinics of North America·2026
Same journal

Imaging Findings after Multidisciplinary Treatment for Orbital and Ocular Adnexal Cancers.

Radiologic clinics of North America·2026
Same journal

Orbital Tumors: What the Radiologist Needs to Know from the Orbital Surgeon's Perspective.

Radiologic clinics of North America·2026
Same journal

Multidisciplinary Management of Tumors of the Orbit.

Radiologic clinics of North America·2026
Same journal

Skull Base, Bone, Pituitary-Regions around Orbit that Affect Vision.

Radiologic clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jun 25, 2025

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

17.6K

Tumor Doubling Time and Screening Interval.

Asha A Bhatt1, Bethany Niell2

  • 1Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA.

Radiologic Clinics of North America
|May 22, 2024
PubMed
Summary
This summary is machine-generated.

Detecting breast cancer early through screening decreases mortality. This review examines breast cancer doubling time by subtype to inform optimal screening intervals, aiding discussions on mammography benefits and drawbacks.

Keywords:
Breast cancer screeningScreening intervalsSojourn timeTumor doubling time

More Related Videos

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
06:23

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Published on: January 12, 2017

14.7K
Detection of Lung Tumor Progression in Mice by Ultrasound Imaging
04:43

Detection of Lung Tumor Progression in Mice by Ultrasound Imaging

Published on: February 27, 2020

6.8K

Related Experiment Videos

Last Updated: Jun 25, 2025

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

17.6K
A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
06:23

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Published on: January 12, 2017

14.7K
Detection of Lung Tumor Progression in Mice by Ultrasound Imaging
04:43

Detection of Lung Tumor Progression in Mice by Ultrasound Imaging

Published on: February 27, 2020

6.8K

Area of Science:

  • Oncology
  • Radiology
  • Public Health

Background:

  • Screening aims to detect curable breast cancers, reducing mortality.
  • Current US screening uses digital mammography and digital breast tomosynthesis.
  • Breast cancer doubling time varies by tumor subtype.

Purpose of the Study:

  • Review breast cancer doubling time across tumor subtypes.
  • Examine how doubling time influences recommended screening intervals.
  • Facilitate informed discussions on mammography screening intervals.

Main Methods:

  • Literature review of breast cancer doubling time studies.
  • Analysis of doubling time data stratified by tumor subtype.
  • Examination of the relationship between doubling time and screening interval recommendations.

Main Results:

  • Doubling times differ significantly among breast cancer subtypes.
  • Tumor subtype influences the optimal frequency for breast cancer screening.
  • Current screening intervals may not be ideal for all subtypes.

Conclusions:

  • Understanding breast cancer doubling time is crucial for personalized screening.
  • Screening intervals should consider tumor biology and growth rate.
  • Further research can refine screening guidelines based on doubling time.