Myopic Regression After FS-LASIK and SMILE

Area of Science:

• Ophthalmology
• Refractive Surgery

Background:

• Myopic regression is a concern after laser vision correction.
• Comparing femtosecond laser-assisted in situ keratomileusis (FS-LASIK) and small-incision lenticule extraction (SMILE) is crucial for understanding long-term outcomes.

Purpose of the Study:

• To compare the degree of myopic regression between FS-LASIK and SMILE over 18 months.
• To identify predictors of myopic regression after these procedures.

Main Methods:

• Retrospective study matching patients by age and preoperative spherical equivalent (SEQ).
• Analysis of myopic regression using Cox proportional hazard model.
• Comparison of outcomes between 416 eyes undergoing FS-LASIK and 416 eyes undergoing SMILE.

Main Results:

• No significant difference in myopic regression between FS-LASIK and SMILE at 18 months.
• Higher myopia and smaller optical zones were significant predictors of myopic regression.
• Cumulative survival rates for myopic regression were comparable between the two procedures at 12 and 18 months.

Conclusions:

• The surgical procedure (FS-LASIK vs. SMILE) does not significantly impact myopic regression.
• Preoperative refractive error and optical zone size are key factors influencing myopic regression.
• Both FS-LASIK and SMILE offer comparable long-term stability regarding myopic regression.