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Incidental finding of Psuedomyxoma Peritonei in Malignant Peripheral Nerve Sheath Tumour
Sana Munir Gill1, Mariyam Waseem1, Humayun Bashir2
1Department of Nuclear Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore.
Abstract:
Psuedomyxoma peritonei is an infrequent clinical entity characterised by intraperitoneal mucinous/gelatinous ascites produced by the cancerous cells. It has been associated with gastrointestinal, gynaecological, lung and breast tumours. It is commonly asymptomatic and is most often detected incidentally on abdominopelvic imaging or laparoscopy. Higher histological grade of the tumour shows increased metabolic activity on 18F-Fluorodeoxyglucose (FDG) positron-emission tomography (PET) computed tomography (CT). It has been rarely reported in patients with sarcoma. We hereby present an interesting case of incidentally diagnosed pseudomyxoma peritonei on 18FDG PET-CT scan of a patient with soft tissue sarcoma of peripheral nerve sheath.
Insights
Pseudomyxoma peritonei, a rare condition of gelatinous ascites, was incidentally found on an 18F-Fluorodeoxyglucose Positron Emission Tomography (FDG PET-CT) scan. This diagnosis occurred in a patient with soft tissue sarcoma of peripheral nerve sheath.
Area of Science:
- Oncology
- Medical Imaging
Background:
- Pseudomyxoma peritonei is a rare condition characterized by mucinous ascites within the peritoneum.
- It is typically associated with gastrointestinal and gynecological malignancies but rarely with sarcomas.
Observation:
- The case involved incidental diagnosis of pseudomyxoma peritonei.
- The diagnosis was made using an 18F-Fluorodeoxyglucose Positron Emission Tomography (FDG PET-CT) scan.
- The patient had a soft tissue sarcoma of peripheral nerve sheath.
Findings:
- Higher histological grade tumors exhibit increased metabolic activity on FDG PET-CT.
- 18FDG PET-CT can detect increased metabolic activity in pseudomyxoma peritonei, even when rare.
- This case highlights pseudomyxoma peritonei in a patient with peripheral nerve sheath sarcoma.
Implications:
- FDG PET-CT can be a valuable tool for incidentally diagnosing rare conditions like pseudomyxoma peritonei.
- This finding expands the known associations of pseudomyxoma peritonei to include peripheral nerve sheath sarcomas.
- Further research may elucidate the specific mechanisms and diagnostic utility of FDG PET-CT in such rare oncological presentations.
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