Double-Sided Tape in Microfluidics: A Cost-Effective Method in Device Fabrication.

Area of Science:

• Biotechnology
• Materials Science
• Medical Diagnostics

Background:

• Increasing demand for affordable, accessible, and reliable research technology.
• Microfluidic devices offer sensitive, specific, and rapid diagnostic tests with minimal sample volumes.
• Traditional fabrication methods (photolithography, soft lithography) are costly and require specialized expertise.

Purpose of the Study:

• To review the use of double-sided tape in microfluidic device fabrication over the past 20 years.
• To highlight the advantages and fabrication techniques of tape-based microfluidics.
• To discuss limitations and potential commercialization of these devices.

Main Methods:

• Review of literature on double-sided tape-based microfluidic devices.
• Analysis of fabrication techniques for creating and bonding microfluidic channels using tape.
• Evaluation of advantages, limitations, and applications.

Main Results:

• Double-sided tape offers a simple, low-cost alternative for microfluidic device fabrication.
• This approach enhances accessibility and reduces production time and cost.
• The review details various tape-based fabrication methods and their suitability for different applications.

Conclusions:

• Double-sided tape-based microfluidics present a viable, cost-effective solution for research and diagnostics.
• This fabrication method facilitates the transition of microfluidic devices from lab to commercial products.
• Further research is needed to address limitations for specific advanced applications.