A Comprehensive Examination of UV-VIS Spectrophotometric Methods in Pharmaceutical Analysis Between 2015-2023

Area of Science:

• Pharmaceutical Analysis
• Analytical Chemistry
• Spectroscopy

Background:

• Quality control in the pharmaceutical industry relies on validated procedures for analyzing active pharmaceutical ingredients and final products.
• Analytical methods, including pharmacopeial and in-house developed techniques, are crucial for pharmaceutical analysis.
• Published research in pharmaceutical analysis attracts significant attention from analysts and researchers.

Purpose of the Study:

• To examine trends in pharmaceutical and bioanalysis studies published between 2015 and 2023.
• To identify future perspectives in pharmaceutical analysis, focusing on UV-VIS spectrophotometry.
• To correlate observed trends with the current state of the pharmaceutical industry.

Main Methods:

• A literature review of pharmaceutical and bioanalysis studies from 2015-2023 was conducted using Google Scholar.
• Studies employing conventional analytical techniques, specifically UV-VIS spectrophotometry, were selected for trend analysis.
• Data on application areas (dosage forms, bulk, pure, biological, herbal) and wavelength ranges were extracted and analyzed.

Main Results:

• UV-VIS spectrophotometry is predominantly used for analyzing pharmaceutical dosage forms (56%), followed by bulk (27%) and pure (16%) materials.
• A significant portion of studies utilized UV-VIS spectrophotometry in the wavelength range of 200-240 nm (28%) and 240-300 nm (27%).
• A notable 44% of studies operated at wavelengths greater than 300 nm, indicating diverse application needs.

Conclusions:

• The study provides valuable insights into the trends of pharmaceutical analysis, particularly the application of UV-VIS spectrophotometry.
• Findings can assist researchers in both industry and academia in anticipating future directions in pharmaceutical analysis.
• The dominance of UV-VIS spectrophotometry for dosage form analysis highlights its continued importance in pharmaceutical quality control.