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Pre-asthma: a useful concept? A EUFOREA paper. Part 2-late onset eosinophilic asthma
G K Scadding1,2, C Gray3,4, D M Conti5,6
1Department of Allergy & Rhinology, Royal National ENT Hospital, London, United Kingdom.
Frontiers in Allergy
|May 30, 2024
Summary
Preventing asthma is crucial. This study explores interventions for individuals at high risk, similar to pre-diabetes management, focusing on late-onset eosinophilic asthma prevention.
Area of Science:
- Allergy and immunology
- Respiratory medicine
- Preventive medicine
Background:
- The concept of pre-diabetes informs strategies for diabetes prevention.
- Pre-asthma, analogous to pre-diabetes, identifies individuals at risk for developing asthma.
- Allergen immunotherapy (AIT) shows promise in preventing asthma in children with allergic rhinitis.
Purpose of the Study:
- To explore preventive strategies for late-onset eosinophilic asthma.
- To investigate potential interventions for individuals at high risk of developing asthma.
- To build upon previous research on pre-asthma and AIT for primary prevention.
Main Methods:
- Review of existing literature on pre-asthma and AIT.
- Exploration of potential interventions for late-onset eosinophilic asthma.
- Analysis of strategies to reduce asthma development in at-risk populations.
Main Results:
- Allergen immunotherapy (AIT) has evidence supporting asthma prevention in children with allergic rhinitis.
- Further research is needed to establish AIT as a primary prevention method for asthma.
- Specific interventions for late-onset eosinophilic asthma require further investigation.
Conclusions:
- Preventive measures, akin to pre-diabetes management, are essential for asthma control.
- Allergen immunotherapy (AIT) is a potential strategy for asthma prevention, particularly in allergic rhinitis.
- Targeted interventions are needed to prevent the development of late-onset eosinophilic asthma.
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