Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.8K
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

1.8K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
1.8K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

386
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
386
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
Allergic Reactions02:06

Allergic Reactions

27.3K
Overview
27.3K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Yao syndrome: Report of 3 cases with a family history.

JAAD case reports·2026
Same author

PRAME Expression and Melanoma In Situ Margin Assessment.

The American Journal of dermatopathology·2026
Same author

Hyperkeratotic Plaque on the Right Hand: Challenge.

The American Journal of dermatopathology·2026
Same author

Hyperkeratotic Plaque on the Right Hand: Challenge.

The American Journal of dermatopathology·2026
Same author

Patient E-Message Character Limit Impact on Primary Care Clinician Burnout.

Journal of the American Board of Family Medicine : JABFM·2026
Same author

An E-cadherin endocytic mutant rescues the severe epidermal p120-catenin null phenotype.

Molecular biology of the cell·2026
Same journal

Care Transitions Continue to Evolve.

The Medical clinics of North America·2026
Same journal

Navigating the Gaps: A Comprehensive Overview of Care Transitions Across the Continuum.

The Medical clinics of North America·2026
Same journal

Care Transitions and Value-Based Payment Models in the United States.

The Medical clinics of North America·2026
Same journal

Technology and Innovation in Care Transitions: Imagining the Future of Postdischarge Care.

The Medical clinics of North America·2026
Same journal

Primary Care, Specialists, and Hospitals: Bridging the Gaps in Communication and Coordination.

The Medical clinics of North America·2026
Same journal

Social Determinants of Health: Unique Considerations in Transitions of Care.

The Medical clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jun 25, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K

Atopic Dermatitis.

Karl T Clebak1, Leesha Helm1, Prabhdeep Uppal2

  • 1Department of Family and Community Medicine, Penn State Health Milton. S Hershey Medical Center, 500 University Drive, H154/C1613 Hershey, PA 17033, USA.

The Medical Clinics of North America
|May 30, 2024
PubMed
Summary
This summary is machine-generated.

Atopic dermatitis (AD) is a chronic inflammatory skin condition causing itchy, red lesions. Effective management focuses on reducing symptoms and skin changes through various treatments.

Keywords:
Atopic dermatitisEmollients and skin carePhototherapySystemic therapyTopical therapy

More Related Videos

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

9.7K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

3.4K

Related Experiment Videos

Last Updated: Jun 25, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

9.7K
A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
08:02

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

Published on: March 24, 2023

3.4K

Area of Science:

  • Dermatology
  • Immunology
  • Inflammatory Diseases

Background:

  • Atopic dermatitis (AD) is a prevalent, chronic inflammatory skin condition.
  • Characterized by erythematous, scaly, and pruritic lesions, often on flexural surfaces.
  • AD follows a relapsing and remitting course.

Purpose of the Study:

  • To outline the key treatment objectives for atopic dermatitis.
  • To provide a comprehensive overview of current therapeutic strategies for AD.
  • To inform clinicians and patients about managing this common skin disease.

Main Methods:

  • Review of established treatment guidelines for atopic dermatitis.
  • Synthesis of information on pharmacological and non-pharmacological interventions.
  • Categorization of therapies including topical, systemic, and phototherapy.

Main Results:

  • Treatment goals emphasize symptom reduction (itching, burning) and improvement of skin integrity.
  • A multimodal approach is recommended, integrating various therapeutic modalities.
  • Therapeutic options range from basic skincare to advanced systemic treatments.

Conclusions:

  • Comprehensive management of atopic dermatitis requires a multifaceted therapeutic strategy.
  • Addressing both the inflammatory process and skin barrier dysfunction is crucial.
  • Current treatments aim to improve quality of life by controlling AD symptoms and progression.