Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

48
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
48
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

37
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
37
Random Variables01:09

Random Variables

11.6K
A random variable is a single numerical value that indicates the outcome of a procedure. The concept of random variables is fundamental to the probability theory and was introduced by a Russian mathematician, Pafnuty Chebyshev, in the mid-nineteenth century.
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
11.6K
Binomial Probability Distribution01:15

Binomial Probability Distribution

10.4K
A binomial distribution is a probability distribution for a procedure with a fixed number of trials, where each trial can have only two outcomes.
The outcomes of a binomial experiment fit a binomial probability distribution. A statistical experiment can be classified as a binomial experiment if the following conditions are met:
There are a fixed number of trials. Think of trials as repetitions of an experiment. The letter n denotes the number of trials.
There are only two possible outcomes,...
10.4K
Probability Distributions01:32

Probability Distributions

6.9K
 The probability of a random variable x  is the likelihood of its occurrence. A probability distribution represents the probabilities of a random variable using a formula, graph, or table. There are two types of probability distribution– discrete probability distribution and continuous probability distribution.
A discrete probability distribution is a probability distribution of discrete random variables. It can be categorized into binomial probability distribution and Poisson...
6.9K
Random Sampling Method01:09

Random Sampling Method

11.0K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest. Among the various sampling methods used by...
11.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A self-powered and reusable biocomputing security keypad lock system based on biofuel cells.

Chemistry (Weinheim an der Bergstrasse, Germany)·2010
Same author

Prevalence of nerve-vessel contact at cisternal segments of the oculomotor nerve in asymptomatic patients evaluated with magnetic resonance images.

Chinese medical journal·2010
Same author

Overexpression and characterization in Bacillus subtilis of a positionally nonspecific lipase from Proteus vulgaris.

Journal of industrial microbiology & biotechnology·2010
Same author

Strategies to minimize variability and bias associated with manual pipetting in ligand binding assays to assure data quality of protein therapeutic quantification.

Journal of pharmaceutical and biomedical analysis·2010
Same author

Medium- and long-chain triacylglycerols reduce body fat and blood triacylglycerols in hypertriacylglycerolemic, overweight but not obese, Chinese individuals.

Lipids·2010
Same author

[The clinical application of 320-slice Computed Tomography (CT) hepatic artery images in patients with liver transplantation].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2010
Same journal

A Quantum Self-Attention Neural Network Model on Quantum Circuits.

IEEE transactions on cybernetics·2026
Same journal

Semi-Explicit Solution of Some Discrete-Time Higher-Order-Cost Mean-Field-Type Control.

IEEE transactions on cybernetics·2026
Same journal

A Novel One-Step Small Object Detector for Autonomous Aerial Vehicles.

IEEE transactions on cybernetics·2026
Same journal

Online Data-Driven-Based Optimal Output Tracking Control Without Initial Stabilizing Policy.

IEEE transactions on cybernetics·2026
Same journal

Digital Redesign-Based Interval State Estimation for Continuous Systems With Aperiodic Discrete Measurements.

IEEE transactions on cybernetics·2026
Same journal

Output Prediction-Based Event-Triggered Interval Estimation for Continuous-Time Switched Systems.

IEEE transactions on cybernetics·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

17.0K

Chance-Constrained Multiple-Choice Knapsack Problem: Model, Algorithms, and Applications.

Xuanfeng Li, Shengcai Liu, Jin Wang

    IEEE Transactions on Cybernetics
    |June 5, 2024
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a new chance-constrained multiple-choice knapsack problem (CCMCKP) for real-world scenarios with unknown weight distributions. A novel data-driven adaptive local search (DDALS) algorithm effectively solves CCMCKP using only sample data.

    More Related Videos

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
    07:35

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

    Published on: October 11, 2018

    7.5K
    Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
    13:04

    Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

    Published on: September 19, 2012

    12.1K

    Related Experiment Videos

    Last Updated: Jun 24, 2025

    Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
    10:58

    Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

    Published on: July 25, 2013

    17.0K
    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
    07:35

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

    Published on: October 11, 2018

    7.5K
    Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods
    13:04

    Measuring the Subjective Value of Risky and Ambiguous Options using Experimental Economics and Functional MRI Methods

    Published on: September 19, 2012

    12.1K

    Area of Science:

    • Operations Research
    • Combinatorial Optimization
    • Data-Driven Optimization

    Background:

    • The multiple-choice knapsack problem (MCKP) is a well-known NP-hard problem with practical applications.
    • A novel variant, the chance-constrained MCKP (CCMCKP), addresses scenarios where item weights are random variables.
    • Existing methods struggle when probability distributions are unknown and only sample data is available.

    Purpose of the Study:

    • To formulate and address the chance-constrained multiple-choice knapsack problem (CCMCKP) under data-driven conditions.
    • To develop a novel algorithm that does not require prior knowledge of weight distributions.
    • To establish benchmark datasets for evaluating CCMCKP solutions.

    Main Methods:

    • Problem formulation for CCMCKP with unknown probability distributions.
    • Development of a data-driven adaptive local search (DDALS) algorithm.
    • Creation of synthetic and real-world telecommunication-based benchmark instances.

    Main Results:

    • The proposed DDALS algorithm demonstrates superior performance compared to existing stochastic and distributionally robust optimization methods.
    • DDALS is effective even with high chance constraint intensity and limited sample data.
    • Experimental results validate the effectiveness of DDALS on both synthetic and application-specific benchmarks.

    Conclusions:

    • DDALS offers a robust and effective data-driven approach for solving CCMCKP without distribution assumptions.
    • The developed benchmark sets and DDALS algorithm provide a foundation for future research in this area.
    • This work advances the practical applicability of knapsack problem variants in uncertain environments.