Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Reticular Dermis01:15

Reticular Dermis

4.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pachy-reticular pseudodrusen associated with pachyvitelliform maculopathy.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

OCT predictors discerning progression to neovascular vs atrophic age-related macular degeneration.

Eye (London, England)·2026
Same author

Real-world durability challenges with nAMD treatments and the potential promise of gene therapy.

Current medical research and opinion·2026
Same author

Idiopathic retinal vasculitis with neovascularisation in Cornelia de Lange syndrome associated with a novel <i>HDAC8</i> variant.

Ophthalmic genetics·2026
Same author

Results from a French brolucizumab access program for pretreated patients with neovascular age-related macular degeneration.

European journal of ophthalmology·2026
Same author

Prognostic Factors in Patients With Submacular Haemorrhage Complicating Age-Related Macular Degeneration: A Post Hoc Analysis of the STAR Study.

Clinical & experimental ophthalmology·2026
Same journal

Congenital Prepapillary Vascular Loops.

Ophthalmology. Retina·2026
Same journal

Lupus Erythematosus Presenting with Ischemic Retinopathy due to Severe Anemia.

Ophthalmology. Retina·2026
Same journal

Bubble Trouble: Preventing Severe Complications after Intraocular Gas Tamponade in Vitreoretinal Surgery.

Ophthalmology. Retina·2026
Same journal

Visual Recovery After Surgery in Epiretinal Membrane Eyes with Retinal Nerve Fiber Layer Schisis and Internal Limiting Membrane Tear.

Ophthalmology. Retina·2026
Same journal

Masquerading disease of macular telangiectasia type 2 - MacTel Project Report No 11.

Ophthalmology. Retina·2026
Same journal

Analysis of Retinal Displacement by Overlay of Infrared Imaging After Pars Plana Vitrectomy for Retinal Detachment Repair: A Multicenter Study.

Ophthalmology. Retina·2026
See all related articles

Related Experiment Video

Updated: Apr 30, 2026

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration
09:24

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration

Published on: March 10, 2023

1.6K

Pachy-Reticular Pseudodrusen.

Riccardo Sacconi1, Giusi Fazzari2, Vittorio Capuano3

  • 1School of Medicine, Vita-Salute San Raffaele University, Milan, Italy; Division of Head and Neck, Ophthalmology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Ophthalmology. Retina
|June 6, 2024
PubMed
Summary
This summary is machine-generated.

Reticular pseudodrusen (RPD) with pachychoroid (pachy-RPD) show more early stages and greater choroidal perfusion compared to RPD without pachychoroid. Pachychoroid may protect against advanced age-related macular degeneration.

Keywords:
Age-related macular degenerationBiomarkerPachychoroidReticular pseudodrusenSubretinal drusenoid deposits

More Related Videos

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.1K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

57

Related Experiment Videos

Last Updated: Apr 30, 2026

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration
09:24

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration

Published on: March 10, 2023

1.6K
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

3.1K
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:38

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

57

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Macular Degeneration

Background:

  • Reticular pseudodrusen (RPD) are a subtype of drusen associated with intermediate age-related macular degeneration (AMD).
  • Pachychoroid, characterized by increased choroidal thickness, is a risk factor for various retinal conditions.

Purpose of the Study:

  • To characterize the features of eyes with reticular pseudodrusen (RPD) and pachychoroid (pachy-RPD).
  • To compare pachy-RPD with eyes exhibiting RPD and normal/leptochoroid (thin choroid).

Main Methods:

  • Retrospective, case-control study of 111 RPD eyes.
  • Eyes were categorized into pachy-RPD (>50 μm choroidal thickness) and control RPD (<250 μm choroidal thickness).
  • Evaluated RPD number and stage, choroidal vascularity index (CVI), and choriocapillaris perfusion density (PD) using OCT and OCT angiography.

Main Results:

  • Pachy-RPD patients were younger (75 vs. 82 years).
  • Pachy-RPD eyes had more early-stage RPD (stage 1) and fewer advanced stages (3 and 4).
  • Pachy-RPD demonstrated significantly higher CVI and choriocapillaris perfusion density.

Conclusions:

  • Pachy-RPD exhibits a distinct RPD stage distribution with more early lesions.
  • Increased choroidal perfusion is observed in pachy-RPD eyes.
  • Pachychoroid may act as a protective factor against the progression of RPD to advanced AMD.