Related Experiment Video
Updated: Jun 24, 2025

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
Postsurgical Pyoderma Gangrenosum After Penile Inversion Vaginoplasty: Case With Review of Diagnostic and Management
Michael M Talanker1, Jessica R Nye1, David T Mitchell1
1Division of Plastic Surgery, Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas.
Postsurgical pyoderma gangrenosum (PSPG) is a rare complication after vaginoplasty. Prompt diagnosis and immunosuppressive treatment led to successful healing without recurrence.
Area of Science:
- Genitourinary Surgery
- Dermatology
- Wound Healing
Background:
- Postsurgical pyoderma gangrenosum (PSPG) is an uncommon ulcerative complication.
- It typically affects breast surgery sites but can occur after other procedures.
Observation:
- A patient developed PSPG 10 days post-penile inversion vaginoplasty.
- Ulcers appeared on perineal wound edges despite an uncomplicated initial recovery.
Findings:
- Treatment with prednisone, cyclosporine, doxycycline, and ciprofloxacin rapidly improved ulceration.
- Immunosuppressive therapy converted purulent ulcers to healthy granulation tissue within 5 days.
Implications:
- This case underscores the need for prompt dermatological consultation for suspected PSPG.
- Early immunosuppression and avoiding further trauma are crucial for managing PSPG after vaginoplasty.
Related Concept Videos
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

