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Updated: May 5, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Digital calibration method to enable depth-resolved all-fiber polarization sensitive optical coherence tomography
Peijun Tang1, Ruikang K Wang1,2, Qing Chao1
1Department of Bioengineering, University of Washington, 3720 15th Ave NE, Seattle, Washington 98195, USA.
This study introduces an all-fiber polarization-sensitive optical coherence tomography (PSOCT) system. It enables depth-resolved birefringent imaging with a single arbitrary input polarization state, simplifying experimental procedures and improving accuracy.
Area of Science:
- Biomedical Optics
- Optical Imaging
- Coherent Tomography
Background:
- Conventional fiber-based polarization-sensitive optical coherence tomography (PSOCT) systems often require complex setups for generating specific input polarization states.
- Pre-adjustment procedures or additional modules are typically needed, limiting system flexibility and user-friendliness.
Purpose of the Study:
- To develop a fully integrated, all-fiber PSOCT system capable of depth-resolved birefringent imaging.
- To eliminate the need for pre-defined input polarization states and simplify experimental procedures.
- To compensate for polarization state changes and polarization mode dispersion (PMD) introduced by optical fibers.
Main Methods:
- Utilized a discrete differential geometry (DDG)-based polarization state tracing (PST) method.
- Employed geometric rotations and transformations in Stokes space for polarization analysis.
- Implemented a calibration target for compensating fiber-induced polarization changes.
- Performed digital compensation for polarization mode dispersion (PMD).
Main Results:
- Achieved depth-resolved birefringent imaging with an arbitrary single input polarization state.
- Successfully compensated for polarization state changes and PMD introduced by optical fibers.
- Demonstrated the system's performance through imaging of a plastic phantom and in vivo skin.
Conclusions:
- The proposed all-fiber PSOCT system offers a simplified, flexible, and user-friendly approach to birefringent imaging.
- The DDG-based PST method effectively mitigates challenges associated with optical fibers in PSOCT.
- The system provides accurate depth-resolved PSOCT imaging results, suitable for various applications.
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