Related Experiment Video
Updated: May 9, 2026

12:44
The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
25.5K
Studies on "Ascites sarcoma"
1The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Summary
Professor Tomizo Yoshida established the Yoshida ascites sarcoma, a pivotal cancer research tool. This monumental work significantly advanced cancer biology and chemotherapy research, inspiring scientific recovery in post-war Japan.
Area of Science:
- Oncology
- Experimental Pathology
- Cancer Research
Background:
- Professor Tomizo Yoshida's seminal 1940s research.
- Development of a rat ascites sarcoma model.
Purpose of the Study:
- To review and celebrate Professor Yoshida's foundational work.
- To underscore the impact of the Yoshida ascites sarcoma on cancer research.
- To highlight its role in post-war scientific resurgence in Japan.
Main Methods:
- Establishment and characterization of a rat ascites sarcoma.
- Publication of findings in a scientific journal.
Main Results:
- Successful creation and detailed description of the Yoshida ascites sarcoma.
- The tumor system became instrumental in advancing cancer biology and chemotherapy.
Conclusions:
- Yoshida's work is a monumental contribution to oncology.
- The ascites tumor model significantly promoted cancer research globally.
- The research inspired scientific activity in Japan during a challenging period.
Related Concept Videos
Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Ascites
DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...

