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Anti-Inflammatory Effect of Herbal Mouthwash Prepared Using Andrographis Paniculata and Rosa Formulation
P Aishvarya Rukmani1, Rajeshkumar Shanmugam1, Pradeep Manigandan1
1Nanobiomedicine Lab, Centre for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Abstract:
Andrographis (A.) paniculata contains andrograpanin, which is both anti-inflammatory and anti-infective. Rosa comprises over 150-200 species from the family Rosaceae. Rosa exerts various properties, including anti-inflammatory property. Herbal mouthwash was made using A. paniculata leaf powder and Rosa extract. The anti-inflammatory effect was evaluated using an albumin denaturation assay and egg albumin denaturation. The percentage of protein denaturation that is inhibited by the formulation of A. paniculata and Rosa indicates that it has strong anti-inflammatory effect. According to the findings, as concentration is raised, the formulation's anti-inflammatory activity rises. The formulation's percentage inhibition values are also equivalent to those of a typical anti-inflammatory medicine, indicating that it may be effective as a natural anti-inflammatory agent.
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