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Biphasic Calcium Phosphate in the Extraction Socket Preservation: A Systematic Review
S Mohanasatheesh1, Anitha Balaji1, Deepa Subramaniam1
1Department of Periodontics and Implantology, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu, India.
Journal of Pharmacy & Bioallied Sciences
|June 17, 2024
Summary
Biphasic calcium phosphate significantly aids socket preservation and bone regeneration after dental extraction. This review analyzed evidence for its use in dental socket healing.
Area of Science:
- Dentistry
- Biomaterials
- Regenerative Medicine
Background:
- Socket preservation is crucial after dental extraction to maintain alveolar bone volume.
- Currently, no single grafting material is universally accepted as standard for socket preservation.
- Biphasic calcium phosphate (BCP) is a potential candidate for socket regeneration.
Purpose of the Study:
- To systematically review and analyze the existing evidence on the efficacy of biphasic calcium phosphate for socket regeneration following dental extraction.
Main Methods:
- A systematic literature search was conducted using PubMed, OVID, and EMBASE databases.
- The search followed a protocol registered with PROSPERO.
- Article screening and evidence synthesis were performed using RAYYAN software.
Main Results:
- The literature search identified 240 articles.
- Only two studies met the inclusion criteria for the systematic review.
Conclusions:
- Biphasic calcium phosphate (BCP), composed of 60% hydroxyapatite (HA) and 40% beta-tricalcium phosphate (β-TCP), demonstrates a significant positive effect on socket preservation.
- BCP also enhances the quality of bone regeneration in dental extraction sockets.
