Related Experiment Video
Updated: Apr 15, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Ceftaroline in CNS and ocular infections: a case series
Emily A Siegrist1, Joseph Sassine2
1Department of Pharmacy, OU Health, OU Medical Center, 700 NE 13th St., Oklahoma City, OK 73104, USA.
Background:
There are limited data describing outcomes of patients treated with ceftaroline for infections with CNS or ocular involvement.
Objectives:
To describe outcomes of patients treated with ceftaroline for methicillin-resistant staphylococcal infections involving the CNS or eye.
Patients And Methods:
This was a retrospective review of 10 patients at an academic medical centre who received ceftaroline for CNS or ocular infections.
Results:
All patients were treated with ceftaroline as part of a combination for salvage therapy. Four patients died, whereas six patients experienced clinical cure. Only one experienced microbiological recurrence.
Conclusions:
These preliminary data suggest that ceftaroline may be an option for salvage therapy of severe staphylococcal infections when used in combination.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Ophthalmic Drug Delivery Systems
Microbiome of the Eye
Viral Meningitis

