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Updated: Jun 23, 2025

Continuous-Wave Propagation Channel-Sounding Measurement System - Testing, Verification, and Measurements
Published on: June 25, 2021
Relationship between transmission/reception conditions of high-frequency plane wave compounding and evaluation
Taisei Higa1, Jeffrey A Ketterling2, Jonathan Mamou2
1Graduate School of Science and Engineering, Chiba University, Yayoicho, Inage, Chiba 263-8522, Japan.
Abstract:
The double-Nakagami (DN) model provides a method for analyzing the amplitude envelope statistics of quantitative ultrasound (QUS). In this study, the relationship between the sound field characteristics and the robustness of QUS evaluation was evaluated using five HF linear array probes and tissue-mimicking phantoms. Compound plane-wave imaging (CPWI) was used to acquire echo data. Five phantoms containing two types of scatterers were used to mimic fatty liver tissue. After clarifying the relationship between the sound field characteristics of the probes and QUS parameters, DN QUS parameters in 10 rat livers with different lipidification were evaluated using one HF linear array probe. For both phantom and in situ liver analyses, correlations between fat content and multiple QUS parameters were confirmed, suggesting that the combination of CPWI using a HF linear array probe with the DN model is a robust method for quantifying fatty liver and has potential clinical diagnostic applications.
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