Effectiveness of Ozonated Water on Gingivitis: A Systematic Review

Area of Science:

• Dental Science
• Periodontology
• Antimicrobial Therapy

Background:

• Ozone is a recognized antibacterial agent with established dental applications.
• Gingivitis is a prevalent oral condition characterized by gum inflammation and bleeding.
• The use of ozonated water as a mouth rinse for gingivitis management requires further investigation.

Purpose of the Study:

• To systematically review the literature on the efficacy of ozonated water in managing gingival inflammation and bleeding.
• To analyze studies published between 2012 and 2023 that utilized ozonated water for gingivitis or gingival bleeding.

Main Methods:

• A systematic literature search was performed in PubMed, MEDLINE, Embase, and Cochrane databases.
• Studies were selected based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
• Five studies met the inclusion criteria for the review.

Main Results:

• The reviewed studies presented varied efficacy of ozonated water in managing gingival health.
• Some studies indicated promising reductions in gingival bleeding and inflammation.
• Other studies suggested limitations when compared to standard treatments like chlorhexidine, with noted methodological heterogeneity.

Conclusions:

• Ozonated water demonstrates potential as an adjunctive therapy for gingival inflammation and bleeding.
• Methodological inconsistencies and lack of standardization across studies limit definitive conclusions.
• Further large-scale, long-term studies with standardized protocols are necessary to establish its clinical effectiveness.