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Ontogeny and Function of Plasmacytoid Dendritic Cells.

Nicholas M Adams1, Annesa Das1, Tae Jin Yun1

  • 1Department of Pathology, New York University Grossman School of Medicine, New York, NY, USA;

Annual Review of Immunology
|June 28, 2024
PubMed
Summary

Plasmacytoid dendritic cells (pDCs) are key innate immune sentinels, recognizing viral nucleic acids to trigger interferon production. This review covers their lineage, viral defense roles, and involvement in systemic lupus erythematosus.

Keywords:
coronavirusdendritic cellsplasmacytoid dendritic cellssystemic lupus erythematosustype I interferon

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