Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Traumatic Memory01:20

Traumatic Memory

83
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
83
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

461
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
461
Dementia01:30

Dementia

110
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
110
Amnesia01:13

Amnesia

117
Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
117
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

31
Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
31
Long-term Depression01:03

Long-term Depression

2.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurorehabilitation for Adults with Brain and Spine Tumors.

Seminars in neurology·2023
Same author

Will ChatGPT Match to Your Program?

American journal of physical medicine & rehabilitation·2023
Same author

Transmission of Bias in the Medical Record Among Physical Medicine and Rehabilitation Trainees.

American journal of physical medicine & rehabilitation·2023
Same author

Atypical Takotsubo Cardiomyopathy Presentation in an Adult Patient.

Journal of community hospital internal medicine perspectives·2022
Same author

Distal Renal Tubular Acidosis in Sjögren's Syndrome: A Case Report.

Cureus·2020
Same author

Feasibility of a Mobile Health Tool for Mothers to Identify Neonatal Illness in Rural Uganda: Acceptability Study.

JMIR mHealth and uHealth·2020
Same journal

Preface.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Pain Unbound: A Comprehensive Review.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Dual Frontiers Cancer and Palliative Care.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Pain Management Across Special Populations: Pediatrics, Geriatrics, and Pregnancy.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Healing from Within: Regenerative Medicine in Pain Therapy.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

The Brain in Pain: Exploring Central Pain Disorders.

Physical medicine and rehabilitation clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2025

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data
06:14

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

Published on: April 18, 2019

6.4K

Chronic Traumatic Encephalopathy.

Allison Wallingford1, Cherry Junn2

  • 1Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.

Physical Medicine and Rehabilitation Clinics of North America
|June 30, 2024
PubMed
Summary
This summary is machine-generated.

This study outlines diagnostic criteria for chronic traumatic encephalopathy (CTE) and traumatic encephalopathy syndrome (TES). It details CTE

Keywords:
Chronic traumatic encephalopathyNeurodegenerative diseaseTauTau proteinTraumatic brain injury

More Related Videos

A Repetitive Concussive Head Injury Model in Mice
05:42

A Repetitive Concussive Head Injury Model in Mice

Published on: October 12, 2016

11.9K
A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila
10:15

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila

Published on: July 4, 2017

8.2K

Related Experiment Videos

Last Updated: Jun 22, 2025

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data
06:14

In Vivo Protocol of Controlled Subconcussive Head Impacts for the Validation of Field Study Data

Published on: April 18, 2019

6.4K
A Repetitive Concussive Head Injury Model in Mice
05:42

A Repetitive Concussive Head Injury Model in Mice

Published on: October 12, 2016

11.9K
A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila
10:15

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila

Published on: July 4, 2017

8.2K

Area of Science:

  • Neuropathology
  • Neurodegenerative Diseases
  • Clinical Neurology

Background:

  • Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive head trauma.
  • Diagnosing CTE has been challenging due to its unique neuropathologic features.
  • Traumatic encephalopathy syndrome (TES) is a proposed clinical diagnosis for suspected CTE.

Purpose of the Study:

  • To present the neuropathologic diagnostic criteria for CTE.
  • To outline the consensus research diagnostic criteria for TES.
  • To differentiate CTE from other neurodegenerative tauopathies.

Main Methods:

  • Review of existing literature on CTE neuropathology.
  • Discussion of diagnostic criteria for CTE.
  • Presentation of preliminary research diagnostic criteria for TES.

Main Results:

  • CTE is characterized by a unique tauopathy pattern distinct from other neurodegenerative diseases.
  • Established neuropathologic criteria aid in CTE diagnosis.
  • Preliminary research criteria for TES offer a framework for clinical diagnosis of suspected CTE.

Conclusions:

  • Neuropathologic criteria are essential for diagnosing CTE.
  • TES criteria represent a significant step towards clinical identification of CTE.
  • Further research is needed to refine TES criteria and their correlation with neuropathologic findings.