Related Experiment Video
Updated: Jun 21, 2025
11:35
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
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Mentalizing self mind but not others: Self-reported mentalization difficulties in multiple sclerosis
Müge Kuzu Kumcu1,2, Zulal Törenli Kaya3, Yasemin Hoşgören Alıcı2,3
1Department of Neurology, Lokman Hekim University, Ankara, Turkey.
Brain and Behavior
|July 6, 2024
Summary
Multiple sclerosis (MS) patients show deficits in understanding others' mental states, impacting social cognition. This study highlights impaired others-based mentalization in MS, suggesting a link to white matter changes.
Area of Science:
- Neuroscience
- Psychology
- Clinical Medicine
Background:
- Mentalization involves interpreting mental states in self and others.
- White matter abnormalities, common in Multiple Sclerosis (MS), may impact mentalization.
- Understanding these effects is crucial for MS patient care.
Purpose of the Study:
- To investigate mentalization skills in patients with Multiple Sclerosis (MS) compared to healthy controls.
- To explore potential links between MS-related white matter changes and mentalization deficits.
Main Methods:
- A comparative study involving 243 participants (73 MS patients, 170 healthy controls).
- Utilized the Mentalization Scale (MentS) to assess different dimensions of mentalization.
- Collected sociodemographic data from all participants.
Main Results:
- MS patients scored significantly lower on the others-based mentalization (MentS-O) dimension.
- No significant differences were found in motivation to mentalize (MentS-M) or self-based mentalization (MentS-S).
Conclusions:
- Multiple Sclerosis patients exhibit difficulties in comprehending others' thoughts and mental states.
- Impaired others-based mentalization may contribute to social cognition challenges in MS.
- Findings suggest a potential neurological basis for social deficits in MS.
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