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Related Experiment Videos

Diffuse mesangial sclerosis--light, immunofluorescent and electronmicroscopy findings.

J Urbach, A Drukker, E Rosenmann

    The International Journal of Pediatric Nephrology
    |April 1, 1985
    PubMed
    Summary

    Familial infantile nephrotic syndrome in a child showed evidence of immune system involvement in kidney disease. This case highlights potential immunologic factors contributing to diffuse mesangial sclerosis.

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    Area of Science:

    • Pediatric Nephrology
    • Immunopathology
    • Renal Histopathology

    Background:

    • Familial infantile nephrotic syndrome (FINS) is a severe kidney disorder.
    • Diffuse mesangial sclerosis (DMS) is a primary cause of FINS.
    • The pathogenesis of FINS/DMS is not fully understood, with genetic factors often implicated.