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Updated: Jun 21, 2025

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Robotic liver parenchymal transection using the SynchroSeal.

Gabriela Pilz da Cunha1,2, Celine De Meyere3, Mathieu D'Hondt3

  • 1Department of Surgery, Amsterdam UMC, Location University of Amsterdam, Amsterdam, The Netherlands.

Surgical Endoscopy
|July 8, 2024
PubMed
Summary

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The novel SynchroSeal device demonstrates safety and effectiveness for robotic liver parenchymal transection. This bipolar electrosurgical tool offers reduced blood loss compared to previous devices in minimally invasive liver surgery.

Area of Science:

  • Minimally Invasive Surgery
  • Hepatobiliary Surgery
  • Surgical Technology

Background:

  • Heterogeneity in instrumentation for liver parenchymal transection in minimally invasive surgery.
  • Lack of dedicated instruments for robotic liver transection.
  • Need to evaluate novel devices for robotic liver surgery.

Purpose of the Study:

  • To assess the safety and effectiveness of the SynchroSeal, a novel bipolar electrosurgical device.
  • To evaluate SynchroSeal performance in robotic liver resection (RLR).

Main Methods:

  • Post-hoc analysis of prospectively collected data from two high-volume centers.
  • Comparison of SynchroSeal with the previous generation Vessel Sealer Extend.
  • Propensity score matching was used for comparison, excluding initial procedures.
Keywords:
Energy deviceMinimally invasive liver surgeryParenchymal transectionRobotic liver surgerySynchroSeal

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Main Results:

  • SynchroSeal showed excellent outcomes in 155 RLRs: low conversion rate (0.6%), minimal blood loss (median 40 mL), short hospital stays (median 3 days).
  • Matched comparison (94 vs 94 patients) revealed significantly less intraoperative blood loss with SynchroSeal (48 mL vs 95 mL, p=0.032).
  • Overall and severe morbidity rates were adequate (19.4% and 11.0% respectively) with SynchroSeal.

Conclusions:

  • The SynchroSeal is a safe and effective device for robotic liver parenchymal transection.
  • SynchroSeal offers advantages in reducing intraoperative blood loss during robotic liver surgery.