Eosinophilic gastroenteritis in an elderly men associated with antibiotic use post maxillofacial space infection: a...

Area of Science:

• Gastroenterology
• Infectious Diseases
• Hematology

Background:

• Maxillofacial space infections can necessitate surgical intervention and antibiotic therapy.
• Post-treatment complications may mimic other systemic diseases, requiring thorough investigation.

Observation:

• A 79-year-old male presented with anorexia, nausea, vomiting, and emaciation following treatment for a maxillofacial space infection.
• Initial investigations revealed elevated inflammatory markers and significant eosinophilia, suggesting a hematological disorder.
• Gastrointestinal endoscopy and histology confirmed eosinophilic gastroenteritis (EGE).

Findings:

• Eosinophilic gastroenteritis (EGE) was diagnosed in a patient initially treated for a maxillofacial space infection.
• The patient exhibited significant eosinophilia and gastrointestinal symptoms.
• Cessation of antibiotics and initiation of corticosteroid therapy led to rapid clinical improvement.

Implications:

• Eosinophilic gastroenteritis (EGE) is a rare condition that should be considered in the differential diagnosis of unexplained gastrointestinal disorders, particularly when accompanied by eosinophilia.
• This case underscores the importance of considering systemic conditions beyond the initial infection site.
• Early diagnosis and appropriate management, including corticosteroid therapy, are crucial for favorable outcomes in EGE.