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Artificial intelligence-based screening for cardiomyopathy in an obstetric population: A pilot study.
Demilade Adedinsewo1, Andrea Carolina Morales-Lara1, Heather Hardway2
1Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
Cardiovascular Digital Health Journal
|July 11, 2024
Summary
Artificial intelligence-enhanced electrocardiograms (AI-ECG) and digital stethoscopes show high accuracy in detecting cardiomyopathy in pregnant and postpartum women. These AI tools offer promising early detection of cardiac dysfunction, improving maternal health outcomes.
Area of Science:
- Cardiology
- Maternal-Fetal Medicine
- Artificial Intelligence in Healthcare
Background:
- Cardiomyopathy is a significant cause of pregnancy-related mortality and a leading cause of death in the postpartum period.
- Delayed diagnosis of cardiomyopathy in obstetric patients is linked to severe adverse outcomes.
Purpose of the Study:
- To assess the diagnostic performance of an artificial intelligence-enhanced electrocardiogram (AI-ECG) and an AI-enabled digital stethoscope for detecting left ventricular systolic dysfunction in obstetric patients.
- To evaluate the effectiveness of AI-powered tools in identifying cardiac dysfunction during pregnancy and postpartum.
Main Methods:
- A prospective, single-arm study involving 100 pregnant and postpartum women.
- Participants underwent standard 12-lead ECG, AI-ECG, digital stethoscope ECG and phonocardiogram recordings, and transthoracic echocardiogram within 24 hours.
- Diagnostic performance was quantified using the area under the curve (AUC).
Main Results:
- The AI-ECG model demonstrated near-perfect classification performance (AUC: 1.0) for detecting cardiomyopathy.
- The AI-enabled digital stethoscope showed high performance (AUC: 0.98 and 0.97) for detecting left ventricular dysfunction.
- Both AI tools achieved 100% sensitivity in identifying cardiac dysfunction.
Conclusions:
- AI-ECG and AI-enabled digital stethoscopes are effective in detecting cardiac dysfunction in the obstetric population.
- These AI technologies show potential for early identification of cardiomyopathy in pregnant and postpartum women.
- Further research, including studies on clinical outcome impact, is warranted.

