Related Experiment Video
Updated: Jun 21, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Synthesis and Characterization of N-Unsubstituted 2- and 3-Furanimines
Amavi Kpoezoun1,2, Houda Gazzeh1, Gnon Baba2
1Univ Rennes, Ecole Nationale Supérieure de Chimie de Rennes, CNRS, ISCR - UMR6226, F-35000 Rennes, France.
Abstract:
N-unsubstituted 2-furanmethanimine and 3-furanmethanimine are the simplest derivatives of an imine family containing numerous drugs. They have been prepared in the gas phase by dehydrocyanation of the corresponding α-aminonitriles, characterized by IR and NMR spectroscopy at low temperature and used in transimination reactions. The kinetic stability of the furanaldimines lies between that of alkylated and arylated derivatives, demonstrating the role played by the substituent. The triethylborane complexes of the aldimines were synthesized by reacting the corresponding nitriles with superhydride.
More Related Videos
10:42Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
11:45Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Related Concept Videos
Nomenclature of Aryl and Heterocyclic Amines
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Overview
Preparation of 1° Amines: Gabriel Synthesis
Strong bases like NaOH or KOH deprotonate the phthalimide to form the corresponding anion, which acts as a nucleophile. Further, the anion attacks an...
Preparation of 1° Amines: Hofmann and Curtius Rearrangement Mechanism
Synthesis of α-Substituted Carbonyl Compounds: The Stork Enamine Reaction
Structure of Amines