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Updated: Jun 21, 2025
Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications
Published on: November 20, 2019
Interplay between materials and microfluidics
Xu Hou1,2,3,4,5, Yu Shrike Zhang1,2,6, Grissel Trujillo-de Santiago1,2,7,8
1Biomaterials Innovation Research Center, Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, Massachusetts 02139, USA.
Microfluidics and advanced materials science are revolutionizing fields from diagnostics to bioengineering. This synergy enables novel materials and complex systems with diverse applications.
Area of Science:
- Interdisciplinary science at the intersection of materials science and microfluidics.
- Focus on inorganic, organic, and hybrid materials for advanced systems.
Background:
- Microfluidics drives innovation across chemical synthesis, electronics, diagnostics, and pharmaceutics.
- Synergy between materials development and microfluidic capabilities fuels rapid growth.
Purpose of the Study:
- Critically evaluate advances in materials fabrication for microfluidic platforms.
- Assess how microfluidics advances materials design and enables new functionalities.
Main Methods:
- Review of inorganic and organic materials for microfluidic systems.
- Exploration of hybrid and modular material configurations.
- Analysis of microfluidic techniques for fabricating new materials.
Main Results:
- Materials enable microfluidic systems with enhanced mechanical, optical, chemical, electrical, and biointerfacial properties.
- Microfluidics facilitates fabrication of functional particles, fibers, 3D (bio)printed composites, and organoids.
- Development of complex, multifunctional systems with biomedical and bioengineering applications.
Conclusions:
- The interplay between materials science and microfluidics expands application diversity.
- Future research will continue to drive innovation in engineering and biomedical sciences.
- This review highlights the transformative potential of integrated materials and microfluidic approaches.
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