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[Breast cancer: Could we consider it as an occupational exposure disease?]
Amelia Favier1, Carole Mathelin2, Maria Gonzalez3
1Service de chirurgie et cancérologie gynécologique et mammaire, hôpital La Pitié-Salpêtrière, AP-HP, Paris, France; Inserm UMR-S 938, biologie et thérapeutiques du cancer, centre de recherche Saint-Antoine (CRSA), institut universitaire de cancérologie (IUC) Sorbonne université, Paris, France.
Objective:
Breast cancer is the leading cancer in women in terms of incidence and mortality. The literature currently identifies several risk factors, some modifiable and others not. Because of its multifactorial nature, the combination of factors either increases or reduces the risk of cancer. Since 2004, the first commission's rapport of the French National Environmental Health Plan has recognized the significant impact of occupational exposure on the development of breast cancer. However, neither primary nor secondary preventive measures have yet been implemented in work environment.
Method:
Based on available literature, we reviewed current knowledge of breast cancer risk factors associated with occupational exposure.
Results:
The risk factors identified were ionizing radiation, magnetic fields, certain endocrine disruptors, ethylene oxide and night shift work.
Conclusion:
Recognition of breast cancer as an occupational disease is complicated. In some cases, however, it may be possible, particularly in cases of multifactorial exposure. This work should help to raise awareness among employers and reinforce preventive measures in the workplace.
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