Related Experiment Video
Updated: Jun 21, 2025

A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
[Renoprotective treatments : renin-angiotensin-aldosterone system blockade and beyond]
1Service de néphrologie-dialysetransplantation, CHU, Nice, France.
Insights
Chronic kidney disease (CKD) management involves dietary changes and medications like renin-angiotensin system blockers. The albumin creatinine ratio (ACR) is a key therapeutic target for slowing disease progression in all CKD patients.
Area of Science:
- Nephrology
- Pharmacology
- Internal Medicine
Renoprotective Treatments:
RENIN-ANGIOTENSINALDOSTERONE SYSTEM BLOCKADE AND BEYOND. Patients with chronic kidney disease (CKD) require both etiological and symptomatic treatments to slow renal function decline. Reductions of protein and salt intakes are required. Pharmacological treatments combines blockade of the renin-angiotensin system, sodium-glucose co-transporter type 2 inhibitors and mineralocorticoid receptor antagonists in most diabetic patients. The albumin creatinine ration (ACR) in morning spot urine samples is now a therapeutic target both in diabetic and non-diabetic CKD patients.
Related Concept Videos
Antihypertensive Drugs: Direct Renin Inhibitors
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antihypertensive Drugs: Angiotensin II Receptor Blockers
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Hormonal Regulation
Heart Failure Drugs: Diuretics

