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Red-shifted two-photon-sensitive phenanthridine photocages: synthesis and characterisation
Célest M Attiach1, Amit Kumar1, Jonathan Daniel2
1Université Paris Cité, CNRS, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, 75006 Paris, France. antoine.maruani@cnrs.fr.
Abstract:
Herein we describe the rational design, synthesis and photophysical study of a novel class of phenanthridine-based, one- and two-photon sensitive, photoremovable protecting groups with absorption wavelengths extending beyond 400 nm. This design facilitated the development of scaffolds with enhanced uncaging quantum yield, paving the way for broader applications in controlled drug delivery and molecular manipulation.
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